Alopecia Areata: How Not to Miss Satoyoshi Syndrome?

October 2014 in “ The Journal of Dermatology ”

Lidia Rudnicka, Małgorzata Kwiatkowska, Adriana Rakowska, Joanna Czuwara, Małgorzata Olszewska

alopecia areata Satoyoshi syndrome autoimmune disorder alopecia totalis antibodies glucocorticosteroids trichoscopy yellow dots muscle spasms diarrhea ANA steroids

Studysummary This paper reviews Satoyoshi syndrome and suggests diagnostic criteria to differentiate its subtypes, emphasizing the importance of testing alopecia areata patients for antinuclear antibodies, muscle spasms, and diarrhea.

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Research cited in this study

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research Role of Trichoscopy in Children's Scalp and Hair Disorders

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This review discusses the use of trichoscopy in diagnosing and managing pediatric hair and scalp disorders and reports no new experimental findings.

research Satoyoshi Syndrome: A Cause of Alopecia Universalis in Association with Neurologic and Bony Abnormalities

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This article shares a case of Satoyoshi syndrome that was misdiagnosed as vitamin D-dependent rickets for several years.

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research Trichoscopy for Common Hair Loss Diseases: Algorithmic Method for Diagnosis

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This study describes characteristic trichoscopic features of various hair loss diseases and proposes an algorithmic method for diagnosing them, but reports no new clinical results.

research Satoyoshi Syndrome: A Rare Multisystemic Disorder Requiring Systemic and Symptomatic Treatment

18 citations , February 2006 in “Brain & development”

This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.

research A Case of Satoyoshi Syndrome: A Multisystem Disorder

13 citations , October 2003 in “Clinical pediatrics”

In this case report, a 14-year-old boy with Satoyoshi syndrome did not improve with intravenous immunoglobulin but responded dramatically to steroid treatment.

research Satoyoshi Syndrome: A Case Study of a 9-Year-Old Thai Girl

12 citations , October 2001 in “Pediatric Dermatology”

This case report describes a 9-year-old Thai girl with Satoyoshi syndrome, where oral corticosteroid therapy significantly improved her painful muscle spasms and alopecia.

research Relative Amounts of Keratin 17 Are Higher Than Those of Keratin 16 in Hair Follicle Derived Tumors Compared to Nonfollicular Epithelial Skin Tumors

31 citations , March 1995 in “Journal of Investigative Dermatology”

research A Case of Syndrome of Progressive Muscle Spasm, Alopecia, and Diarrhea (Satoyoshi) Treated with Steroid Pulse Therapy

16 citations , June 1992 in “PubMed”

In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.

research A Case of Generalized Komuragaeri Disease (Satoyoshi Disease) Treated with Glucocorticoid

19 citations , January 1991 in “PubMed”

This case study reported that glucocorticoid treatment markedly improved all clinical features in a girl with generalized komuragaeri disease, suggesting potential autoimmune involvement in the disease's pathogenesis.