Effectiveness and Safety of Topical Finasteride for Male Androgenetic Alopecia: Real World Data

    March 2026 in “ International Journal of Dermatology ”
    Bianca Maria Piraccini, Luca Rapparini, Federico Quadrelli … Michela Starace
    Studysummary In this study, topical finasteride 0.25% showed sustained effectiveness over 52 weeks, especially in the frontotemporal areas of men with androgenetic alopecia, while maintaining an excellent safety profile.
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    Research cited in this study 10

    1. Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment Drug Design Development and Therapy · 2025
    2. Is the Safety of Finasteride Correlated With Its Route of Administration: Topical Versus Oral? A Pharmacovigilance Study With Data From the United States Food and Drug Administration Adverse Event Reporting System International Journal of Dermatology · 2025
    3. No Increased Risk of Mood Disorders in Male Androgenetic Alopecia Patients Treated with Dutasteride and Finasteride: A Retrospective Cohort Database Study Journal of the American Academy of Dermatology · 2025
    4. Painful Bilateral Gynecomastia Secondary to Topical Finasteride Australasian Journal of Dermatology · 2024
    5. Patient-Reported Outcomes of Topical Finasteride/Minoxidil Treatment for Male Androgenetic Alopecia: A Retrospective Study Using Telemedical Data Journal of cosmetic dermatology · 2024
    6. What's New in Therapy for Male Androgenetic Alopecia? American Journal of Clinical Dermatology · 2022
    7. Topical Finasteride for Male and Female Pattern Hair Loss: Is It a Safe and Effective Alternative? Journal of Cosmetic Dermatology · 2022
    8. Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
    9. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    10. A Hair Growth Questionnaire for Use in the Evaluation of Therapeutic Effects in Men Journal of Dermatological Treatment · 1998