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July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study investigates the potential of onion extract as a treatment for androgenetic alopecia by using in silico and ADME/T analyses to examine how active compounds from onions interact with the 5-alpha-reductase enzyme.
May 2026 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this study, topical red onion ethanol extract significantly restored cutaneous antioxidant and pro-angiogenic markers in UV-B-exposed rats, enhancing SOD and VEGF levels dose-dependently, but did not influence hair length, suggesting potential as an adjunct for hair photoaging.
January 2020 in “JoLS Journal of Life Sciences” This study found that a mixture of Red-BCQ and Agnex extract promoted greater hair growth and antioxidant effects in C57BL/6 mice compared to other groups, including minoxidil treatment.
October 2025 in “World Journal of Advanced Research and Reviews” This review reports that topical applications of onion-based preparations, like onion juice and oil, may support hair regrowth in patchy alopecia areata and improve scalp health through antioxidant and antimicrobial effects, although standardized formulations and clinical trials are limited.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that onion-derived products, like juice and oil, show potential benefits for hair regrowth in alopecia areata and scalp health due to their rich phytochemical content, but notes that further standardized formulations and rigorous clinical trials are needed to substantiate these effects.