Oral Tofacitinib in Refractory Pediatric Alopecia Areata

    July 2025 in “ International Journal of Trichology ”
    Priyadarshini Mishra, Namrata Nidhi, Binayak Chandra Dwari, Nibedita Patro
    Studysummary This study reported that six out of seven pediatric patients with refractory patchy alopecia areata experienced significant hair regrowth after one month of oral tofacitinib treatment, suggesting it may be an effective and safe option, although larger studies are needed to evaluate long-term safety.
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    Research cited in this study 7

    1. Effectiveness of Tofacitinib in Pre-Adolescent Alopecia Areata: A Retrospective Case Series and Literature Review Acta dermato-venereologica · 2023
    2. Clinical Response to Oral Tofacitinib in Pediatric Patients With Alopecia Areata JAAD Case Reports · 2022
    3. Oral Tofacitinib for the Treatment of Alopecia Areata in Pediatric Patients Pediatric Dermatology · 2021
    4. Treatment of Pediatric Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2021
    5. Treatment of Alopecia Areata in Pre-Adolescent Children with Oral Tofacitinib: A Retrospective Study Pediatric Dermatology · 2020
    6. Efficacy and Safety of Tofacitinib Therapy in Asian Patients with Severe Alopecia Areata Dermatologica Sinica · 2020
    7. Tofacitinib for the Treatment of Alopecia Areata in Preadolescent Children Journal of the American Academy of Dermatology · 2018