Amelioration of Psoriasis-Like Skin Lesions by Human Amniotic Mesenchymal Stem Cells: Insights from Multiomics Profiling in Mice

    February 2026 in “ Frontiers in Immunology
    Liehao Yang, Baihui Miao, Qian Sun, Fangqing Zhang, Hongyan Sun, Zilong Zhou, Yue Hu, Zhiming Cui, D. Y. Wang, Chenlu Liu, Liang Zhang, Qianying Hu, Xianling Cong
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    Studysummary This study found that administering human amniotic mesenchymal stem cells (hAMSCs) in a mouse model of psoriasis improved skin lesions and reduced inflammation-related markers, suggesting potential therapeutic benefit and safety for treating psoriasis, and identified specific gene targets involved in the treatment's mechanism.
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