Developing and Validating an HPLC Method to Quantify Simultaneously Dutasteride and Their Related Molecules (Dutasteride Acid, 2,5 Bis-(Trifluoromethyl)-Aniline and Dutasteride 17 α-Epimer) in Capsules

    Pola Srinivas, Kancharlapalli Venkataramana
    Studysummary This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.
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    Research cited in this study 4

    1. Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction Hormone Molecular Biology and Clinical Investigation · 2017
    2. Superiority of Dutasteride Over Finasteride in Hair Regrowth and Reversal of Miniaturization in Men With Androgenetic Alopecia: A Randomized Controlled Open-Label, Evaluator-Blinded Study Indian Journal of Dermatology, Venereology and Leprology · 2016
    3. Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review PubMed · 2016
    4. A Method to Monitor Dutasteride in Rat Plasma Using Liquid-Liquid Extraction and Multiple Reaction Monitoring: Comparisons and Validation Mass spectrometry letters · 2014

    Related research 1

    1. Discovery and Clinical Development of Dutasteride, a Potent Dual 5α-Reductase Inhibitor Current topics in medicinal chemistry · 2006