Successful Management of Therapy-Resistant Chronic Refractory Atopic Dermatitis and Alopecia Universalis With Oral Tofacitinib in a Girl

    October 2025 in “ International Journal of Risk & Safety in Medicine ”
    Shreya K Gowda, Bhini Ameta, Akash Agarwal, Biswanath Behera
    Studysummary In this case study, a 5-year-old girl with alopecia areata and atopic dermatitis that were unresponsive to previous treatments achieved substantial improvement with long-term tofacitinib, highlighting its potential safety and efficacy in managing both conditions concurrently.
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    Research cited in this study 3

    1. Effectiveness of Tofacitinib in Pre-Adolescent Alopecia Areata: A Retrospective Case Series and Literature Review Acta dermato-venereologica · 2023
    2. Treatment of Alopecia Areata in Pre-Adolescent Children with Oral Tofacitinib: A Retrospective Study Pediatric Dermatology · 2020
    3. Simultaneous Improvement of Alopecia Universalis and Atopic Dermatitis in a Patient Treated with a JAK Inhibitor JAAD case reports · 2018

    Related research 6

    1. Steroid-Free Monotherapy with Tofacitinib in Severe Therapy-Resistant Alopecia: A Retrospective Analysis Indian Dermatology Online Journal · 2023
    2. Alopecia Universalis Treated With Tofacitinib: The Role of JAK/STAT Inhibitors in Hair Regrowth Cutis · 2023
    3. Alopecia Areata Flare Patterns in Children and Young Adults on Systemic Tofacitinib Journal of the American Academy of Dermatology · 2021
    4. Brazilian Experience of Treating Alopecia Universalis with Novel Antirheumatic Therapy Tofacitinib: A Case Series Rheumatology and Therapy · 2017
    5. Alopecia Universalis Successfully Treated With Tofacitinib Journal of the American Academy of Dermatology · 2017
    6. Excellent Response to Tofacitinib Treatment in a Patient with Alopecia Universalis Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.) · 2017