Neuro-Inspired Biomimetic Microreactor for Sensory Recovery and Hair Follicle Neogenesis Under Skin Burns

    November 2023 in “ ACS Nano ”
    Qin Zhao, Jinyang Wang, Shen Qu … Yufeng Zhang
    Studysummary In a mouse model of deep skin burns, this study found that a neuro-inspired biomimetic microreactor, when delivered through a hydrogel and activated by near-infrared light, significantly promoted functional skin regeneration, sensory recovery, and hair follicle formation.
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    Research cited in this study 8

    1. Design of a Biofluid-Absorbing Bioactive Sandwich-Structured Zn–Si Bioceramic Composite Wound Dressing for Hair Follicle Regeneration and Skin Burn Wound Healing Bioactive Materials · 2020
    2. Regeneration of Skin Appendages and Nerves: Current Status and Further Challenges Journal of Translational Medicine · 2020
    3. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    4. External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway Proceedings of the National Academy of Sciences of the United States of America · 2018
    5. Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2017
    6. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    7. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    8. Live Imaging of Smad2/3 Signaling in Mouse Skin Wound Healing Wound repair and regeneration · 2007

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