Hair for the Long Haul: Alopecia Areata Cases and Considerations

    December 2025 in “ Dermatology The American Medical Journal ”
    Helen Boreham
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Baricitinib →

    JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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    Studysummary In this conference session, experts reviewed clinical evidence and strategies for using JAK inhibitors in managing alopecia areata, emphasizing optimal treatment practices and individual patient considerations to enhance safety and effectiveness in real-world settings.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    At the 2025 Fall Clinical Dermatology Conference, experts discussed the long-term management of alopecia areata (AA) using JAK inhibitors, which have significantly changed the treatment landscape. Three JAK inhibitors—baricitinib, ritlecitinib, and deuroxolitinib—are now approved for use. The session focused on real-world case examples to address key management considerations such as treatment eligibility, dose adjustment, response monitoring, and patient counseling. The goal was to fill knowledge gaps and improve clinical decision-making to ensure the safe and effective use of JAK inhibitors in treating AA.
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