Cepharanthine Dry Powder Inhaler for the Treatment of Acute Lung Injury

    May 2023 in “ Molecules ”
    Di Liang, Wanmei Wang, Guangrui Chen … Ruolan Gu
    Studysummary In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.
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    Research cited in this study 5

    1. Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury Pharmaceutics · 2022
    2. Bioavailability Enhancement of Cepharanthine via Pulmonary Administration in Rats and Its Therapeutic Potential for Pulmonary Fibrosis Associated with COVID-19 Infection Molecules · 2022
    3. Evaluating Cepharanthine Analogues as Natural Drugs Against SARS-CoV-2 FEBS Open Bio · 2021
    4. Cepharanthine: A Review of the Antiviral Potential of a Japanese-Approved Alopecia Drug in COVID-19 Pharmacological Reports · 2020
    5. Cepharanthine: An Update of Its Mode of Action, Pharmacological Properties, and Medical Applications Phytomedicine · 2019