Would Dut be enough against TRT?
    8/8/2026

    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Dutasteride (oral) 1.5mg 1 month
    💊 Minoxidil (oral) 2.5mg 1 month
    💧 RU58841 (topical)
    the tone is 😐 neutral.

    Other terms

    Using 1.5mg dutasteride, 2.5mg oral minoxidil, and topical RU58841 may help manage hair loss while on testosterone, but regrowth is uncertain. Users report varying success with different dosages and combinations of these treatments.
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    6 / 6 results

      community Can a test cycle cause hairloss with 2.5 mg dutasteride?

       3 upvotes 8 months ago
      Increasing dutasteride to 2.5 mg daily and adding 2.5 mg oral minoxidil to prevent hair loss during a testosterone cycle. Suggestions include adding RU58841 for better protection against hair loss.

      community Very high free testosterone on dut…

       9 upvotes 6 months ago
      The user has high free testosterone and is still experiencing hair loss despite taking dutasteride and oral minoxidil for over three years. They are considering adding a topical anti-androgen like RU58841.

      community My hair loss makes no sense I can't stand it

       30 upvotes 1 year ago
      A user experienced severe hair loss after taking testosterone, despite using treatments like Dutasteride, RU58841, and Minoxidil. The user regrets taking testosterone, as it seems to have permanently increased sensitivity to DHT, accelerating hair loss.

      community Can I take bicalutamide for hair loss as a man, but don’t want to transition?

      in Treatment  4 upvotes 6 months ago
      A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.

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    6 / 6 results