Aromatase Upregulation along with DHT down regulation could possibly hold the cure
    Microneedling 5/10/2022

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 17α Estradiol (topical) 0.05%/0.1% 3 years
    💧 RU58841 (topical)
    the tone is 😐 neutral.

    Other terms

    The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.
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      community Could RU58841 actually worsen hairloss?

      in Treatment  2 upvotes 6 months ago
      The user experienced worsening hair density after using finasteride, dutasteride, and RU58841, suspecting RU58841 might be the cause. They are considering stopping RU58841 after a scalp biopsy, while others share mixed experiences with RU58841's effectiveness.

      community Can aromatase inhibitors make dutasteride/finasteride useless?

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      The conversation discusses using aromatase inhibitors with dutasteride or finasteride for hair loss, which can prevent testosterone from turning into estrogen but may lead to increased DHT and potentially make finasteride less effective. There's concern about proper dosing and side effects like gynecomastia and emotional changes.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 4 days ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

      community Does DHT give you a leaner face?

      in Finasteride/Dutasteride  44 upvotes 6 months ago
      Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.

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