Research and Question about Allopregnanolone, Multiple Sclerosis, TRT, and Finasteride Finasteride/Dutasteride 11/7/2022
A 52-year-old male with Multiple Sclerosis is considering using Finasteride and Testosterone Replacement Therapy (TRT) for hair loss but is advised to lose weight first to avoid side effects. He is currently focusing on diet, weight loss, and using Rogaine and microneedling for hair treatment.
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5 / 111 resultscommunity How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that
Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.
community Completely defeated after trying so hard with topical finasteride.
A user who has tried multiple treatments for hair loss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.
community 22M started fin/min/dermaroller again after stopping for almost 2 years (2months progress)
A 22-year-old resumed using finasteride, minoxidil, and a 0.5mm dermaroller after stopping for two years, experiencing positive results and improved mood. The discussion includes debates on the effects of finasteride on neurosteroids and the optimal dermaroller needle length for hair regrowth.
community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
community Started Finasteride almost three months ago and I'm upset
A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.
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