Hair transplants and PP405 - Irregular density concern 3/26/2026
The conversation discusses concerns about getting a hair transplant with the potential release of a new treatment, PP405, which may regrow dormant hair follicles. The user is currently using Minoxidil, Derma, and Keto but is waiting to start finasteride or dutasteride.
View this post in the Community →
Similar Community Posts Join
5 / 5 resultscommunity Say this new supposed miracle drug “PP405” does actually cure baldness, how will that affect people with hair transplants?
PP405 may reactivate dormant hair follicles but won't replace hair transplants or resurrect dead follicles. Its effectiveness, cost, and impact compared to treatments like minoxidil and finasteride are uncertain.
community Reminder: NURTURE those dormant hair follicles for as long as you can until PP405 comes out in 2028-2030
PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.
community If PP405 does revive "dead" hair follicles would DHT blockers theoretically be enough to maintain that new hair
PP405 may revive dormant hair follicles, and DHT blockers like finasteride or dutasteride could maintain new hair. Combining PP405 with minoxidil might be optimal, but long-term effects and continuous use are uncertain.
community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"
Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.
community Is PP405 gonna flop or what???
PP405 is viewed skeptically, with some seeing it as overhyped and potentially ineffective compared to existing treatments like minoxidil and finasteride. While it shows some promise in activating dormant hair follicles, many believe it won't replace hair transplants or significantly outperform current options.
Related Research
6 / 6 resultsresearch Health Utility Measures Among Patients with Androgenetic Alopecia After Hair Transplant
This study found that alopecia significantly lowers patients' quality of life compared to laypeople's perception, with hair transplantation improving quality of life more for male patients than commonly perceived.
research ПОРІВНЯЛЬНИЙ АНАЛІЗ МЕТОДІВ ВІДНОВЛЕННЯ ВОЛОССЯ В УКРАЇНІ ТА США
This research provides a comprehensive comparison of hair restoration methods used in Ukraine and the USA, examining the effectiveness of surgical and non-surgical treatments for alopecia, including FUE and FUT hair transplantation, PRP therapy, and low-level laser therapy.
research Oestrogen functions in skin and skin appendages
This review discusses the influence of oestrogens on various skin components and highlights their modulatory roles and receptor pathways, but it reports no new clinical results.
research Outcome of intra-operative injected platelet-rich plasma therapy during follicular unit extraction hair transplant: A prospective randomised study in forty patients
This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.
research The effects of autologus platelet rich plasma and various growth factors on non-transplanted miniaturized hair
This small study observed that infusing platelet rich plasma into the scalp reversed hair miniaturization and stimulated new hair growth in patients with androgenetic alopecia and alopecia areata over 8 months.
research Effects of Finasteride (1 mg) on Hair Transplant
In this study of men with androgenetic alopecia, daily finasteride 1 mg alongside hair transplant improved scalp hair density and growth of nontransplanted hair compared to placebo over 48 weeks.