Finasteride and naturally low baseline DHT levels? 7/30/2022
A user discovered they have naturally low DHT levels and is concerned about taking finasteride, which could further lower these levels. They are seeking advice on whether to proceed with the treatment given their hormone levels are within the normal range.
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6 / 6 resultscommunity Is ED after taking Fin or Dut caused by less DHT or an increase in Estrogen/Estradiol
Finasteride and dutasteride may cause erectile dysfunction due to reduced DHT, affecting nitric oxide and sexual function. Some suggest using aromatase inhibitors to address side effects, while others believe individual sensitivity to DHT reduction varies.
community DHT Isn't (Directly) Important
Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.
community DHT results after 1 year on dutasteride, confused and seeking guidance
The user is experiencing rapid hair loss despite using dutasteride, finasteride, and minoxidil, and is concerned about high estradiol and testosterone levels. They are advised to consult an endocrinologist for potential hormonal imbalances.
community 17-alpha-estradiol/Alfatradiol how does it Work for Hair loss?
17-alpha-estradiol may work for hair loss by inhibiting 5-alpha reductase, similar to finasteride. It might lower testosterone in the scalp, reducing DHT conversion.
community 5-Months Update: Minoxidil + Red Light Therapy + Lifestyle Changes
The user reported positive hair regrowth after 5 months using Minoxidil, red light therapy, and lifestyle changes, including dietary improvements and stress reduction. They chose natural supplements like saw palmetto and beta-sitosterol over pharmaceutical DHT inhibitors like finasteride.
community Testosterone and Estradiol levels on 1 mg/day dutasteride
A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.
Related Research
6 / 6 results
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines
In this study, researchers developed a sensitive assay to measure the inhibition of steroid 5-α reductase (5AR) by chemicals like finasteride and dutasteride, revealing species-specific differences in inhibitor efficacy between human and fish cell lines.
research Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase
This review examines the pharmacological properties and potential clinical benefits of 5α‐reductase inhibition in prostate cancer but reports no new research findings.
research Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride
In this study, co-administration of finasteride with oral testosterone undecanoate in young men with induced hypogonadism had no significant effect on serum testosterone or dihydrotestosterone levels, likely due to TU's unique absorption route.
research Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia
Clinical studies reported that finasteride reduces scalp dihydrotestosterone levels and improves hair growth in men with androgenetic alopecia, supporting its role as a treatment option.
research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
This study identified LY191704 as a specific noncompetitive inhibitor of human 5 alpha-reductase type 1, which may be useful in treating endocrine disorders related to DHT overproduction.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
This review discusses various targets for treating prostate cancer and benign prostatic hyperplasia and reports on recent studies of new compounds and 5α-reductase inhibitors, but provides no new experimental results.