Do drugs actually work for diffuse thinning?
    Treatment 4/4/2026

    From the encyclopedia
    Finasteride →

    Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

    Dutasteride →

    5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

    Minoxidil →

    Vasodilator used on the scalp and, at low doses, as a tablet

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    šŸ’Š Finasteride (oral) 1 mg daily 14 months
    šŸ’Š Dutasteride (oral) 0.5 mg twice a week 8 months
    šŸ’Š Minoxidil (oral) 2.5 mg daily 8 months
    the tone is šŸ˜ž negative.

    Other terms

    The user is treating diffuse thinning with finasteride, dutasteride, and oral minoxidil but hasn't seen significant improvement. Others suggest that results vary, with some maintaining hair and others considering transplants or future treatments.
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    Related Research

    6 / 6 results

      research Safety concerns when using novel medications to treat alopecia

      23 citations , October 2018 in “Expert Opinion on Drug Safety”
      This review discusses the safety concerns associated with new treatments for non-scarring alopecias, highlighting that while these therapies such as JAK inhibitors and oral minoxidil show efficacy in hair regrowth, their safety profiles vary significantly, requiring careful consideration of benefits and risks.

      research Primary cicatricial alopecia

      95 citations , November 2016 in “Journal of The American Academy of Dermatology”
      This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.

      research Managing patterned hair loss – a hair raising task!

      October 2021 in “Cosmoderma”
      This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.

      research Minoxidil: a comprehensive review

      16 citations , June 2021 in “Journal of Dermatological Treatment”
      This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.