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research Formulation and Evaluation of Polyherbal Antidandruff Shampoo

July 2024 in “Anti-Infective Agents”

This study explored the development of a herbal anti-dandruff shampoo using natural polyherbal tincture and reported strong antimicrobial effects, which suggests it may be a safer and more effective alternative to conventional solutions that can cause side effects like hair loss and irritation.

research Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

7 citations , October 2023 in “European Journal of Pharmacology”

This study found that Cannabidivarin (CBDV) promotes neuronal differentiation and inhibits oligodendrocyte maturation via TRPV1 modulation, highlighting its potential in neural stem cell research.

research Phytochemical profiling, green synthesis of Ag, Cu, Fe, and Zn nanoparticles, and in vitro biological activities of Delphinium brunonianum Royle

May 2026 in “Scientific Reports”

This study explored the phytochemical profile of Delphinium brunonianum, reporting that its extracts and synthesized nanoparticles demonstrated significant radical scavenging, enzyme inhibition, and antimicrobial activities, suggesting future potential in medical applications.

research Aberrant Wnt signalling induces comedo-like changes in the upper hair follicle

1 citations , October 2020 in “Research Square (Research Square)”

This study found that abnormal Wnt signalling in stem cells may contribute to blackhead formation in acne by inhibiting cell differentiation and causing cell accumulation in the junctional zone.

research OPTIMIZATION OF NANO GEL FORMULATION BASED ON BANGKAL (NAUCLEA SUBDITA) WOOD BARK EXTRACT AND ANTIBACTERIAL ACTIVITY AGAINST PROPIONIBACTERIUM ACNES

1 citations , May 2025 in “International Journal of Applied Pharmaceutics”

This study formulated a nanogel with Bangkal bark extract that showed moderate antibacterial activity against Propionibacterium acnes, with the F3 formulation (8% extract) achieving the highest inhibition zone of 8 mm, suggesting potential as a natural acne treatment.

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community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle

1 upvotes 1 year ago

The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.

community Does age play a role in how you respond to 5AR inhibitors? (finasteride/dutasteride)

in Research/Science 24 upvotes 2 years ago

The conversation discusses whether age affects the side effects and effectiveness of hair loss treatments like finasteride and dutasteride. Some believe early treatment yields better results, while others mention varied outcomes across ages and personal regrowth experiences without a clear consensus on age impact.

community Will PP405 render Minox and Fin obsolete?

30 upvotes 1 year ago

PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.

community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

community Finasteride, Neurosteroids, and Neuroplasticity - have you noticed cognitive shifts or have you continued growing?

in Basic Questions 201 upvotes 3 months ago

The conversation discusses concerns about potential cognitive and emotional effects of finasteride, with the original poster planning to monitor their cognitive performance while using the treatment. A user responds that most people do not experience cognitive shifts, though some report subtle changes.

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