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GlossaryXenografts

transplantation of tissues or organs between different species

Xenografts, also known as xenotransplants, refer to the transplantation of cells, tissues, or organs from one species to another. For example, using pig skin grafts to treat human burn victims. This technique is often explored in medical research to address the shortage of human donors for organ transplants and to study disease mechanisms.

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research Non-Thermal Acoustic Enhancement of Chemotherapeutic Effects of Cisplatin on Xenografted Cervical Cancer in Mice

November 2023 in “Anticancer Research”

Using ultrasound may make cisplatin more effective against cervical cancer in mice.

research A Nude Mouse Model of Hypertrophic Scar Shows Morphologic and Histologic Characteristics of Human Hypertrophic Scar

47 citations , November 2012 in “Wound repair and regeneration”

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

research Carotid Body Tumor: Review of the Literature and Report of a Case With Rare Sensorineural Symptomatology

10 citations , June 2007 in “Journal of Oral and Maxillofacial Surgery”

A man's rare tumor caused unusual nerve-related symptoms that improved after surgery.

research Study of the Behavior of Lesional and Nonlesional Skin of Canine Recurrent Flank Alopecia Transplanted to Athymic Nude Mice

2 citations , July 2013 in “Veterinary dermatology”

Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.

research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

522 citations , January 2001 in “Cancer investigation”

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

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community Is it possible to transplant mice skin into human body?

in Transplants 47 upvotes 1 month ago

Transplanting mice skin to humans is not feasible due to immune rejection, but some suggest genetic modification or immune suppression could make it possible. Xenograft hair transplants are discouraged.

community Expectations control for SCUBE3

in Research/Science 20 upvotes 1 year ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community This is the best time in human history to be fighting hair loss

in Treatment 189 upvotes 3 years ago

This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.