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research Crystal Structure and Synthesis of 17.ALPHA.-Acetoxy-6,7-epoxypregn-4-ene-3,20-dione

1 citations , January 2009 in “X-ray Structure Analysis Online”

A new compound was made that might help treat diseases related to male hormones.

research Structural characterization of polymorphs and molecular complexes of finasteride

17 citations , January 1999 in “Journal of Molecular Structure”

This study determined the molecular structure of finasteride and its related crystalline forms, highlighting different hydrogen-bond interactions and structural configurations in various crystalline complexes.

research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family

October 2019

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

research Structural studies of two solid steroid compounds

2 citations , January 2006 in “Durham e-Theses (Durham University)”

This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.

research Giant axonal neuropathy alters the structure of keratin intermediate filaments in human hair

8 citations , April 2017 in “Journal of The Royal Society Interface”

This study found that keratin intermediate filaments in the hair of GAN patients are altered, showing decreased diffraction signals and increased stiffness, strength, and extensibility.

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community Say this new supposed miracle drug “PP405” does actually cure baldness, how will that affect people with hair transplants?

201 upvotes 1 year ago

PP405 may reactivate dormant hair follicles but won't replace hair transplants or resurrect dead follicles. Its effectiveness, cost, and impact compared to treatments like minoxidil and finasteride are uncertain.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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