September 2026 in “Journal of Biophotonics” This study indicates that microwave-assisted Opuntia humifusa extract combined with Red-LED irradiation may better modulate intracellular redox status and Wnt/β-catenin-related protein expression in human hair follicle dermal papilla cells than each treatment alone.
February 2025 in “Frontiers in Veterinary Science” This study found that keratin hydrolyzed, egg yolk lecithin, and fish collagen peptide promoted β-catenin nuclear translocation and increased gene expression related to hair regeneration in canine and cat skin cell lines, suggesting these nutrients may help improve hair regeneration in pets.
September 2025 in “Stem Cells Translational Medicine” This study found that exosomes from human umbilical cord stem cells, pretreated with lithium chloride, significantly enhance hair regeneration in mice by activating the Wnt signaling pathway through miR-146a-5p.
18 citations
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July 2021 in “Molecular Medicine Reports” This review summarizes existing knowledge of how the WNT signaling pathway affects mesenchymal stem cells under various conditions, highlighting challenges and mechanisms for clinical applications.
8 citations
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September 2017 in “Journal of Investigative Dermatology” This study found that inhibiting the interaction between CXXC5 and Dishevelled could stimulate hair regrowth in mouse models by enhancing WNT/β-catenin signaling, suggesting a potential therapeutic strategy for hair loss involving compounds that block this interaction, such as interfering short peptides.