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Sensitive Quantitative In Vivo Assay for Evaluating the Effects of Biomolecules on Hair Growth and Coloring Using Direct Microinjections into Mouse Whisker Follicles

research Sensitive Quantitative In Vivo Assay for Evaluating the Effects of Biomolecules on Hair Growth and Coloring Using Direct Microinjections into Mouse Whisker Follicles

July 2023 in “Biomolecules”

The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.

research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1

33 citations, February 1999 in “The journal of investigative dermatology/Journal of investigative dermatology”

IGF-1 increases whisker growth in transgenic mice.

research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss

86 citations, July 2020 in “International Journal of Molecular Sciences”

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

research Transcriptome Analysis of Improved Wool Production in Skin-Specific Transgenic Sheep Overexpressing Ovine β-Catenin

4 citations, January 2019 in “International journal of molecular sciences”

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes

research Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes

6 citations, November 2010 in “Histochemistry and cell biology”

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

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Community Join

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community Seems I have acquired progressive kinking of the hair, potentially brought on by minox.

11 upvotes 7 years ago

User experienced hair kinking after starting minoxidil, despite being on finasteride for two years. Another user confirmed similar issues and suggested switching brands due to propylene glycol in minoxidil.

community Just quit nicotine and caffeine

in Treatment 21 upvotes 2 years ago

The user has been using finasteride and oral minoxidil for hair loss but hasn't seen improvement and is quitting nicotine and caffeine to see if it helps. Some believe quitting nicotine improved their hair health due to better blood flow, while others are skeptical about the impact of blood flow on hair loss.

community Anyone else growing tired of the finasteride wars?

in Finasteride/Dutasteride 169 upvotes 1 year ago

The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

community Did anybody not care at all about their hair until they started losing it?

in Chat 134 upvotes 1 month ago

People regret neglecting their hair until it started thinning, and they are now using treatments like finasteride, minoxidil, and microneedling. Some are considering stronger options like dutasteride due to mixed results.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

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