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Glossary Western blot

laboratory technique to detect specific proteins in samples

Western blot, also known as protein immunoblot, is a laboratory technique used to detect specific proteins in a sample. It involves separating proteins by gel electrophoresis, transferring them to a membrane, and then using antibodies to identify the target protein. This method is widely used in research and diagnostics to study protein expression and function.

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research Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes

58 citations , December 2000 in “Experimental Dermatology”

This study found that new rabbit antisera against recombinant mouse involucrin effectively marked keratinocyte differentiation, with comparable expression patterns to human involucrin.

research Lack of androgen receptor transcriptional activity in human keratinocytes

30 citations , June 2000 in “Journal of dermatological science”

In this study, researchers found that keratinocytes are unlikely to be target cells for androgen, as shown by limited androgen receptor transcriptional activity in keratinocyte cells.

research Angiogenin is expressed in human dermal papilla cells and stimulates hair growth

20 citations , October 2008 in “Archives of dermatological research”

This study found that angiogenin is expressed in human dermal papilla cells, where it might stimulate hair growth by promoting cell proliferation and local skin angiogenesis.

research Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata

19 citations , January 2018 in “Scientific Reports”

This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.

research Expression of bioactive recombinant human fibroblast growth factor 9 in oil bodies of Arabidopsis thaliana

16 citations , August 2015 in “Protein Expression and Purification”

This study found that recombinant human FGF9 expressed in Arabidopsis thaliana oil bodies significantly promoted the proliferation of NIH/3T3 cells.

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community Day 1 vs 6 months vs 1 year vs 2 years. Finasteride, minoxidil and derma rolling.

2749 upvotes 1 year ago

A user documented their two-year hair regrowth journey using finasteride, minoxidil, and derma rolling, showing significant improvement. They switched from topical to oral minoxidil after the first year, experiencing some shedding and minor bloating.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

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