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Dutasteride can significantly reduce sperm volume, with some users experiencing up to a 90% decrease. While some users report adaptation over time, others suggest switching to finasteride if side effects are too severe.

Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

The conversation is about trying Hair Volume by New Nordic for improving hair quality and density. The product contains biotin, apple extract, millet extract, L-methionine, pantothenic acid, silicon, zinc oxide, and copper sulfate.

Long-term use of dutasteride may impair semen volume and sperm motility, but these effects are often reversible after stopping the drug. Individual reactions vary, and more research is needed to understand the long-term impact on fertility.

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.