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research Cerebral Ischemia Related to Isotretinoin; Venlafaxine-Induced Alopecia; Cognitive Dysfunction with Tolterodine; Retinal Artery Occlusion after Injection of Long-Acting Risperidone; Olanzapine-Induced Chylomicronemia Presenting as Pancreatitis; Metabolic Effects of the Atypical Antipsychotics – an Editorial; Another Drug-Induced Pancreatitis – This One Caused by a Tyrosine Kinase Inhibitor; Suicide Attempts Related to Antidepressant Medications

November 2007 in “Hospital pharmacy”

This article discusses the importance of increasing awareness about specific adverse drug reactions, prevention methods, and the promotion of reporting ADRs to the FDA's MEDWATCH program; it reports no new results.

research Fluoxetine- and Sertraline-Related Hair Loss in a Teenager: A Case Report

5 citations , February 2013 in “Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology”

This case report observed that an adolescent female experienced hair loss with fluoxetine and sertraline, which resolved with venlafaxine, suggesting potential alopecia as an adverse reaction to these SSRIs.

research Chemically Induced Hair Loss/Alopecia

January 2019 in “Springer eBooks”

This review discusses drugs and mechanisms possibly responsible for chemical- and drug-induced hair loss but presents no new research findings.

research Venlafaxine induced hair loss: a case report

2 citations , February 2016 in “Düşünen Adam”

This case report suggests that venlafaxine may cause hair loss in some patients, as demonstrated by a patient whose hair loss ceased after stopping the medication.

research Alopecia associated with agomelatine use: a case report

2 citations , June 2017 in “Psychiatry and clinical psychopharmacology”

This case report describes the first known instance of hair loss linked to agomelatine, which resolved after the drug was discontinued.

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Community Join

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community Hair loss over a year following depression and taking antidepressants

in Side effects? 200 upvotes 8 months ago

A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

community How an SSRI seemed to help my hairloss

7 upvotes 3 years ago

An SSRI (paroxetine) reduced hair loss and itching for a user with male-pattern baldness, but liver issues forced discontinuation, leading to increased hair loss and anxiety. The user plans to try other anti-anxiety medications, noting stress and anxiety significantly impact hair loss.

community Could Finasteride theoretically induce chronic telogen effluvium?

5 upvotes 1 year ago

A user experienced continuous hair shedding for 13 months after starting finasteride, suspecting it might cause chronic telogen effluvium, and considered switching to dutasteride or stopping medication. Other users suggested that finasteride doesn't cause hair loss, recommending dutasteride for more aggressive hair loss, while some advised against stopping medication.

community Massive shed after starting a caffeine shampoo? Am panicking.

4 upvotes 5 years ago

The user experienced significant hair shedding after starting a caffeine shampoo called Alpecin, despite being on finasteride and switching to dutasteride. The doctor suggested the shedding might be due to new hair growth, while others speculated it could be from switching medications or the shampoo's ineffectiveness.

community Alfatradiol causing shedding ?

1 upvotes 1 year ago

The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.

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Learn

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learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

What is valproic acid, and how did it become a subject of interest in hair growth and alopecia research? Valproic acid is a prescription anticonvulsant that laboratory and mouse studies link to the Wnt/β-catenin hair-growth pathway; one small randomized trial of an 8.3% topical spray reported a hair-count gain over 24 weeks. Oral valproate is also a recognized cause of hair loss and a known teratogen.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.
What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.
What are the key limitations and considerations surrounding tofacitinib in hair loss products and therapies? Reported hair regrowth with tofacitinib comes from alopecia areata, an autoimmune condition — mostly from small, non-randomized studies, with relapse common after stopping. There is no good evidence it helps pattern hair loss, and it is not approved for hair loss anywhere.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

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