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GlossaryUltraviolet A damage (UVA damage)

harm from deep-penetrating UVA rays causing skin aging and cancer

Ultraviolet A (UVA) damage refers to the harm caused by UVA radiation, a type of ultraviolet light from the sun that penetrates deep into the skin. This damage can lead to premature aging, DNA mutations, and an increased risk of skin cancer. UVA rays are less intense than UVB rays but are more prevalent and can penetrate through clouds and glass, making them a significant concern for long-term skin health.

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research Effect of Conditioned Media Collected from Human Amniotic Fluid-Derived Stem Cells on Skin Regeneration and Photo-Aging

9 citations, February 2014 in “Tissue Engineering and Regenerative Medicine”

Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.

research RPGRIP1L Facilitates Desmosomal Adhesion Through Suppressing PKCβII-Mediated Desmoglein Endocytosis: Implication in Pemphigus

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor

research Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.

research Fullerene Nanoparticles in Dermatological and Cosmetic Applications

101 citations, October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine”

Fullerenes show potential in skin care but need more safety research.

research Protective Role of Melatonin and Its Metabolites in Skin Aging

32 citations, January 2022 in “International Journal of Molecular Sciences”

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

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community Sucess story for you guys, pics are 10+ years apart.

in Progress Pictures 311 upvotes 8 months ago

A user shared a success story showing hair regrowth over 10 years, attributing it to quitting creatine and taking 0.5mg finasteride. Some commenters were skeptical about creatine's impact, while others inquired about side effects, and the original poster reported no negative effects from finasteride.

community 5 month update on my all natural protocol

in Update 7 upvotes 6 years ago

The user updated on their all-natural hair loss protocol, which includes massages, LLLT, Ashwagandha, Supergreens mix, Vitamin D, Castor Oil + DMSO, a specific diet, and headstands. They reported some hair regrowth and improved hair quality, with plans to continue the regimen and monitor results.

community So does oral minoxidil age your skin or not

in Minoxidil 41 upvotes 7 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community When I’m 60 and finally off the fin after 40 years and look at my semen

in Satire 862 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Users share experiences with Finasteride, mentioning watery semen as a side effect and weighing its importance against maintaining hair.

community Thoughts on this procyanidin B2 supplement?

in Product 6 upvotes 1 year ago

User found 15% procyanidin B2 supplement and asks if it's legit. Recommended dosage is 400-600mg daily, similar to study, and user wonders if it's effective for hair loss.

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