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research Low‐level laser activates Wnt/β‐catenin signaling pathway‐promoting hair follicle stem cell regeneration and wound healing: Upregulate the expression of key downstream gene Lef 1

2 citations , June 2024 in “Skin Research and Technology”

This study found that low-level laser stimulation activates the Wnt signaling pathway, promoting hair follicle stem cell regeneration and accelerating wound healing.

research Presence of Uterine Leiomyomas Has No Significant Impact on Gene Expression Profile in the Scalp of Patients with Central Centrifugal Cicatricial Alopecia

2 citations , October 2021 in “JID innovations”

This study found no significant gene expression differences in the lesional scalp of patients with central centrifugal cicatricial alopecia with and without a history of uterine leiomyomas.

research Hairless Up‐Regulates Tgf‐β2 Expression via Down‐Regulation of miR‐31 in the Skin of “Hairpoor” (Hr^Hp) Mice

11 citations , January 2015 in “Journal of cellular physiology”

This study suggests that abnormal hair cycles in Hr mutant mice may be caused by HR protein overexpression, which down-regulates miR-31 and increases Tgf-β2 expression.

research Stromal Vascular Fraction and Platelet-Rich Plasma Upregulate Vascular Endothelial Growth Factor Expression to Promote Hair Growth via the Wnt/β-Catenin Signaling Pathway

2 citations , December 2019 in “Nanoscience and Nanotechnology Letters”

In a study on the effects of stromal vascular fraction (SVF) and platelet-rich plasma (PRP) on hair growth in nude mice, researchers found that both treatments promoted hair growth, with SVF showing a stronger effect.

research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling

13 citations , September 2022 in “Biomolecules”

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

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community Can Tazarotene Upregulate Minoxidil Conversion Like Tretinoin?

in Minoxidil 2 upvotes 1 year ago

Tazarotene's potential to enhance Minoxidil conversion, similar to Tretinoin, is questioned. Users discuss the lack of information and seek further details.

community Do we know exactly why some people respond so great to dut/fin,min and others dont?

in Research/Science 29 upvotes 1 year ago

Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.

community Can I take finasteride and creatine both daily?

20 upvotes 2 years ago

Creatine may accelerate genetic hair loss, but stopping it can reverse the effects. Finasteride helps block DHT, and some users report no issues taking both daily.

community Stop buying sketchy Thai oral minox online. You guys are literally paying $80 for chalk in a zip-lock bag

4 upvotes 1 month ago

Avoid buying unregulated Thai oral minoxidil online due to quality and safety concerns; instead, get a prescription for legitimate, tested minoxidil from a pharmacy. Some users also use finasteride and ketoconazole for hair loss treatment.

community Sugar and Hair loss connections

in Research/Science 41 upvotes 1 year ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

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