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mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
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2 / 2 resultslearn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
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research The Degradative Characteristics of Hair in Water Samples with Altered pH
Hair fibers degrade and change color in very basic water.
research Re-Innovation in Clinical Trial Designs Based on Precision Therapy
Clinical trials should use innovative designs and biomarkers to improve precision therapy and patient outcomes.
research The Charnoly Body as a Universal Biomarker of Cell Injury
Charnoly bodies could be a marker for cell damage, and certain nutrients and proteins might prevent them, potentially helping with brain diseases and cancer.
research A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification
The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.
research Efficacy and Safety of Tofacitinib in Patients With Total and Universal Alopecia: A Retrospective Evaluation of 69 Patients
Tofacitinib is effective for treating alopecia totalis and universalis, with some patients experiencing significant hair regrowth.
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5 / 166 resultscommunity AGA evaluation and first steps - BEGINNER MEGAPOST
The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.
community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.
Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.
community People treat you way nicer when you have hair, I didn’t believe it until it happened to me
Having hair improves social interactions and treatment by others, with hair transplants and finasteride enhancing confidence and attractiveness. People often receive more positive attention after addressing hair loss.
community Why do we get bald from evolutionary perspective
Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.
community C’est terrible - at my wits end
A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.