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    GlossaryAlopecia Universalis

    complete loss of all body and scalp hair

    Alopecia Universalis (AU) is a severe form of alopecia areata characterized by the complete loss of hair on the scalp and body, including eyebrows and eyelashes. It is an autoimmune condition where the immune system mistakenly attacks hair follicles, leading to total hair loss.

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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community Losing hair everywhere, idk what to do :(

       29 upvotes 5 years ago
      A 22-year-old male has been experiencing widespread hair loss for over four years, including pain and significant shedding. Treatments tried include ketoconazole shampoo, fluocinonide topical solution, biotin, ACV, and dry shampoo, but none have been effective.

      community AGA evaluation and first steps - BEGINNER MEGAPOST

      in Chat  76 upvotes 3 months ago
      The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community C’est terrible - at my wits end

      in Female  449 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.