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research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

119 citations , November 2016 in “American journal of human genetics”

This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.

research Uncombable hair syndrome: Observations on response to biotin and occurrence in siblings with ectodermal dysplasia

101 citations , July 1985 in “Journal of the American Academy of Dermatology”

In this study, oral biotin improved hair growth, strength, and combability in a child with uncombable hair syndrome, while hair in two others slowly improved without biotin.

research Familial Uncombable Hair Syndrome: Ultrastructural Hair Study and Response to Biotin

49 citations , April 2007 in “Pediatric Dermatology”

This study describes a family with uncombable hair syndrome, suggesting autosomal dominant inheritance, and reports that oral biotin improved hair appearance in two young patients.

research Uncombable hair (pili trianguli et Canaliculi): Evidence for dominant inheritance with complete penetrance based on scanning electron microscopy

33 citations , September 1987 in “American Journal of Medical Genetics”

This study documents dominant transmission and complete penetrance of uncombable hair syndrome in a family, despite the father lacking visible abnormalities.

Crystalline Cataract and Uncombable Hair Syndrome in a 7-Year-Old Girl

research Crystalline Cataract and Uncombable Hair

26 citations , September 1990 in “Ophthalmology”

This case study found that a 7-year-old girl's crystalline cataract had sulfur-containing amino acids likely cystine, and was associated with abnormal hair conditions.

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community Fellas how jealous are we? I would harvest an organ for this set of lettuce.

1680 upvotes 1 year ago

The conversation humorously discusses a person with an unusually thick head of hair, with some users joking about using treatments like Minoxidil and finasteride. Many express envy or disbelief, while others suggest a haircut or comment on facial features.

community Over 95% of his face is covered in hair.

in Satire 349 upvotes 1 year ago

A young man with hypertrichosis has over 95% of his face covered in hair, sparking humorous comments about hair loss treatments like minoxidil and dutasteride. Users joke about transplanting his facial hair and discuss the challenges of his condition compared to typical balding.

community If all these vellus hairs turn terminal I’m gonna be a chewbacca

92 upvotes 6 months ago

The user is using minoxidil, finasteride, dermarolling, and other treatments for hair regrowth, showing promising results in the temple area. Despite some skepticism, there is optimism about potential improvement.

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