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GlossaryUltra-Performance Liquid Chromatography Tandem Mass Spectrometry

advanced technique for separating and identifying compounds in samples

Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry (UPLC-MS/MS) is an advanced analytical technique used to separate, identify, and quantify compounds in a sample. UPLC enhances the resolution and speed of liquid chromatography, while MS/MS provides highly sensitive and specific detection by breaking down molecules into fragments and analyzing their mass. This method is widely used in fields like pharmacology, biochemistry, and environmental science for precise and accurate analysis of complex mixtures.

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Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

research Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

1 citations , February 2014 in “Analytical Letters”

The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.

Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

research Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

10 citations , January 2019 in “Journal of Chromatography B”

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

1 citations , April 2015 in “Drug research”

New method measures finasteride in plasma, finds two formulations bioequivalent.

research A Quantitative Ultra-Performance Liquid Chromatography High-Resolution Mass Spectrometry Analysis of Steroids from Human Scalp Hair

7 citations , April 2022 in “Journal of pharmaceutical and biomedical analysis”

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

research Profiling Steroid and Thyroid Hormones with Hair Analysis in a Cohort of Women Aged 25 to 45 Years Old

6 citations , February 2022 in “European journal of endocrinology”

The method can measure multiple hormones in women's hair and may help identify hormone-related health issues.

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community 2 year fin/min progress (age 27-29)

in Progress Pictures 302 upvotes 2 years ago

A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hair loss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.

community Fin+Colostrum: My journey is a little different.

in Is this regrowth? 14 upvotes 10 months ago

The user has been using finasteride for 30 years and recently added colostrum to their routine, noticing darker hair regrowth. They experienced shedding with minoxidil and advise against its use, while highlighting the benefits and side effects of long-term finasteride use.

community I don’t understand this, is he equating taking Fin with being on HRT?

in Finasteride/Dutasteride 305 upvotes 2 months ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community So...why does switching from fin to dut ruin people's hair?

in Finasteride/Dutasteride 77 upvotes 9 months ago

Switching from finasteride to dutasteride can cause hair shedding, with mixed results; some see improvement, others see worsening. Using both treatments together initially may help reduce shedding.

community How Dangerous is Oral Min Really?

in Minoxidil 26 upvotes 10 months ago

Oral minoxidil is generally effective for hair loss but may cause side effects like heart palpitations and facial puffiness. Users highlight the importance of monitoring blood pressure due to potential cardiovascular risks.

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