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GlossaryUltra Performance Liquid Chromatography

Ultra Performance Liquid Chromatography (UPLC) is an advanced form of liquid chromatography that allows for faster and more efficient separation of chemical compounds in a mixture. It uses smaller particles and higher pressures than traditional High-Performance Liquid Chromatography (HPLC), resulting in better resolution, sensitivity, and speed, which is particularly useful in fields like pharmaceuticals, environmental testing, and biological research.

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Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

research Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

10 citations , January 2019 in “Journal of Chromatography B”

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

research Determination of 13 Janus Kinase Inhibitors in Anti-Alopecia Cosmetics by Ultra-High Performance Liquid Chromatography-Tandem Triple Quadrupole Composite Linear Ion Trap Mass Spectrometry

September 2025 in “Chinese Journal of Chromatography”

A new method accurately detects illegal JAK inhibitors in hair loss cosmetics.

research Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

January 2019

Researchers developed a quick and accurate method to measure hormones in urine, confirming a baldness treatment's effectiveness without altering hormone levels.

research A Quantitative Ultra-Performance Liquid Chromatography High-Resolution Mass Spectrometry Analysis of Steroids from Human Scalp Hair

7 citations , April 2022 in “Journal of pharmaceutical and biomedical analysis”

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

research Studies on the Persistence of Estradiol Benzoate and Nortestosterone Decanoate in Hair of Cattle Following Treatment with Growth Promoters, Determined by Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

18 citations , April 2009 in “Journal of Chromatography A”

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

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community 2 year fin/min progress (age 27-29)

in Progress Pictures 302 upvotes 2 years ago

A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hair loss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.

community Fin+Colostrum: My journey is a little different.

in Is this regrowth? 14 upvotes 10 months ago

The user has been using finasteride for 30 years and recently added colostrum to their routine, noticing darker hair regrowth. They experienced shedding with minoxidil and advise against its use, while highlighting the benefits and side effects of long-term finasteride use.

community My Testosterone results before and after Finasteride

in Update 149 upvotes 4 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community I don’t understand this, is he equating taking Fin with being on HRT?

in Finasteride/Dutasteride 300 upvotes 2 months ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community So...why does switching from fin to dut ruin people's hair?

in Finasteride/Dutasteride 77 upvotes 9 months ago

Switching from finasteride to dutasteride can cause hair shedding, with mixed results; some see improvement, others see worsening. Using both treatments together initially may help reduce shedding.

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