research Ultrahigh-Power Sonicator Lysis Enables Deep ProteomicProfiling of Hair Shafts for Fetal Growth Restriction Biomarker Discovery
This study developed a new method using ultrahigh-power sonication and mass spectrometry to improve protein extraction from hair shafts, identifying 239 differentially expressed proteins related to fetal growth restriction, which were validated as potential noninvasive biomarkers for perinatal diagnostics.