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GlossaryThiazolidinediones (TZDs)

medications that increase insulin sensitivity to treat type 2 diabetes

Thiazolidinediones, also known as TZDs or glitazones, are a class of medications primarily used to treat type 2 diabetes. They work by increasing the body's sensitivity to insulin, thereby helping to control blood sugar levels. These drugs activate a specific receptor called PPAR-gamma, which influences the regulation of glucose and lipid metabolism.

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research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology

84 citations, February 2015 in “Experimental Dermatology”

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

1265 citations, October 2013 in “The Journal of Clinical Endocrinology and Metabolism”

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

research Dermatologic Manifestations of Polycystic Ovary Syndrome

76 citations, January 2007 in “American Journal of Clinical Dermatology”

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

research Polycystic Ovary Syndrome: Diagnosis and Treatment

73 citations, February 2007 in “The American Journal of Medicine”

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

research A Clinical Approach to Severe Insulin Resistance

32 citations, January 2007 in “KARGER eBooks”

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

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