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    Glossary Type III Collagen

    Type III collagen is a fibrillar collagen that plays a crucial role in the structural integrity of various tissues, including skin, blood vessels, and hair follicles. It is particularly relevant to hair biology as it contributes to the extracellular matrix of the dermal papilla, which is essential for hair follicle development and cycling. Distinguishing characteristics of type III collagen include its ability to form reticular fibers, providing support and elasticity, and its presence in tissues undergoing rapid growth or repair, making it significant in the context of hair loss and regeneration.

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    1. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    2. Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy Journal of Investigative Dermatology · 2013 · 27 citations
    3. Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation Tissue & Cell · 2019 · 11 citations
    4. Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway Frontiers in Cell and Developmental Biology · 2026
    5. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    6. Identification of a human type XVII collagen fragment with high capacity for maintaining skin health Synthetic and systems biotechnology · 2024
    7. Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis 2017
    8. Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
    9. Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
    10. [Effects of collagen type ⅩⅦ α1 on epidermal stem cells in aging skin and the microRNA intervention mechanism]. PubMed · 2022
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