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Research

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research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle

139 citations , December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.

research K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1

130 citations , April 2003 in “Journal of Investigative Dermatology”

This study reports the cloning and expression details of two new human type II keratins, K6irs3 and K6irs4, in the hair follicle's inner root sheath, suggesting a distinct functional role related to hair structure.

research Structure of human type II 5 alpha-reductase gene.

124 citations , September 1992 in “Endocrinology”

This article discusses the structure of the human type II 5 alpha-reductase gene and reports no new experimental results.

research Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with polycystic ovary syndrome

100 citations , June 2002 in “Diabetologia”

This study found that parents of women with PCOS have a higher prevalence of insulin resistance and Type II diabetes than parents of healthy women.

research A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix

100 citations , November 1997 in “Human Genetics”

In this study, researchers found that the prevalent Glu 410 Lys mutation in hHb6 and a new Glu 403 Lys mutation in hHb1 are linked to monilethrix, suggesting a mutational hotspot in type II hair keratins.

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Community Join

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community He is claiming, he can treat alopecia

in Chat 357 upvotes 8 months ago

A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.

community I stopped finasteride and minoxidil and I regret it

in Progress Pictures 251 upvotes 4 months ago

The user regrets stopping finasteride and minoxidil due to increased hair loss. They have resumed these treatments and are considering a hair transplant.

community KX-826 1% Phase II Results from China Just Dropped

37 upvotes 1 year ago

KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 3 years ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell

13 upvotes 11 years ago

A new treatment using dermal sheath cup cells may regrow hair and could require repeat treatments every 8 years. Users discuss ongoing trials and plan to use finasteride and minoxidil until the treatment is available.

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Learn

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learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

learn Fluocinolone

What type of hair loss is Fluocinolone recommended for, and how does it help inflamed scalps? Fluocinolone is a prescription topical corticosteroid used for inflammatory scalp conditions such as seborrheic dermatitis, scalp psoriasis and scarring alopecias. It calms inflammation rather than growing hair, it is not a treatment for pattern hair loss, and its labelling warns against prolonged use.

learn Hair Transplant

What type of anesthesia is used for hair transplants? Hair transplants are typically performed under local anesthesia with optional sedation.
What type of hair transplant is best for me? Consult a hair surgeon to determine the best transplant type for your needs.

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