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    Research 10 of 1000+

    1. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    2. Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss Journal of The American Academy of Dermatology · 1999 · 46 citations
    3. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride Hormone Molecular Biology and Clinical Investigation · 2010 · 45 citations
    4. Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia Expert Opinion on Investigational Drugs · 1999 · 32 citations
    5. Luteinizing Hormone and Human Chorionic Gonadotropin Decrease Type 2 5α-Reductase and Androgen Receptor Protein Levels in Women’s Skin The Journal of Clinical Endocrinology & Metabolism · 1998 · 13 citations
    6. Upregulation of mir-1199-5p is associated with reduced type 2 5-α reductase expression in benign prostatic hyperplasia BMC Urology · 2022 · 6 citations
    7. Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting Annals of medicine and surgery · 2022
    8. Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study BMJ. British medical journal · 2019 · 29 citations
    9. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone. Biochemical Pharmacology · 2001 · 22 citations
    10. Absence of Interaction Between 5α‐Reductase Inhibitors and Glucocorticoids on Incidence of Myocardial Infarction in People With Type 2 Diabetes Diabetes Obesity and Metabolism · 2026
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    Community 10 of 84

    1. 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that? Reddit · 3 Oct 2024
    2. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    3. FCE 28260: A Forgotten 5α-Reductase Inhibitor Community · 22 Aug 2024
    4. Was scared to try fin and jumped straight to 2.5mg Dut? Reddit · 12 Sept 2026
    5. 5ar Type I in the frontal hair follicles - Dutasteride Reddit · 30 Apr 2024
    6. Thoughts on this Article: Post-Finasteride and Neurological Effects Reddit · 16 Mar 2024
    7. The truth about Dutasteride (w/ sources) Reddit · 24 Jan 2023
    8. Whats up with all the dutasteride destroying hair posts Reddit · 12 May 2023
    9. Connection between finasteride and nafld? Reddit · 13 Aug 2024
    10. DHT and 5AR respect post, it's importance within the brain Reddit · 3 Mar 2024
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    Learn 4 of 6

    1. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    2. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    3. Neem Oil Oil from the neem tree, used in traditional remedies
    4. Bicalutamide Nonsteroidal anti-androgen, originally a prostate cancer drug
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