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research Pernicious anemia in a patient with Type 1 diabetes mellitus and alopecia areata universalis

15 citations , November 2009 in “Journal of diabetes and its complications”

This case highlights the potential link between type 1 diabetes, pernicious anemia, and alopecia areata universalis, suggesting clinicians should monitor for pernicious anemia in such patients.

Pharmacokinetic Parameters and Mechanisms of Inhibition of Rat Type 1 and 2 Steroid 5α-Reductases: Determinants for Different In Vivo Activities of GI198745 and Finasteride in the Rat

research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.

22 citations , October 2001 in “Biochemical Pharmacology”

This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.

research Autoimmune polyendocrine syndrome type 1: an Italian survey on 158 patients

31 citations , May 2021 in “Journal of endocrinological investigation”

This study in Italy found that APS-1, a rare disorder, is associated with various AIRE gene mutations and most individuals have autoantibodies such as IFNωAbs, which are markers of the condition.

research Dermatologic Effects of Selumetinib in Pediatric Patients with Neurofibromatosis Type 1: Clinical Challenges and Therapeutic Management

15 citations , March 2024 in “Journal of Clinical Medicine”

In this four-year study, pediatric patients with inoperable plexiform neurofibromas and type 1 neurofibromatosis treated with selumetinib frequently experienced dermatologic side effects, which required tailored management strategies and sometimes led to treatment suspension, potentially affecting tumor regrowth.

Role of Plasminogen Activator Inhibitor Type 1 (PAI-1) in PCOS Patients

research Role of plasminogen activator inhibitor type 1 (PAI-1) in PCOS patient

3 citations , August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology”

This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.

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Learn

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learn Hair Transplant

Can a diabetic patient undergo a hair transplant? Diabetic patients can have hair transplants if their condition is well-controlled.
Who is a good candidate for a hair transplant? Good candidates for hair transplants have sufficient donor hair and stable hair loss patterns.
How should I care for my hair after a hair transplant? Follow your doctor's aftercare instructions, avoid sun exposure, and use gentle shampoo.
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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Stem Cell Factor

learn Thymosin Beta 4

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community Hormonal panel after 1 year of treatment - DHT levels doubled!!

7 upvotes 2 years ago

A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community 1 Year on Fin Vs. Dut | Be patient

128 upvotes 1 year ago

The user switched from finasteride to dutasteride for stronger hair loss treatment, despite initial success with finasteride. They experienced significant shedding with dutasteride but remain hopeful for regrowth, emphasizing patience and the importance of giving treatments time to work.

community Just got a dermastamp, and it is FAR superior to a roller. I’ll never go back.

in Microneedling 99 upvotes 2 years ago

A user switched from a 1.5 mm derma roller to an adjustable dermastamp for microneedling to treat hair loss and found it less painful and more effective. Some users prefer different depths and tools like the Dr.Pen for microneedling, while others debate the necessity of depth and tool type.

community My Pyrilutamide Experience Update 2, Part 1

63 upvotes 3 years ago

The user's experience taking Pyrilutamide, a drug for hair loss treatment, and their use of it in combination with other treatments such as Minoxidil, Finasteride and RU58841. They have experienced positive results so far with no major side effects.

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