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Did you mean Trichilemmal Cysts?

GlossaryTrichilemmal Cysts

non-cancerous, keratin-filled lumps typically found on the scalp

Trichilemmal cysts, also known as pilar cysts, are non-cancerous, fluid-filled lumps that typically develop on the scalp. They originate from the outer root sheath of hair follicles and are filled with keratin, a protein found in hair, skin, and nails. These cysts are usually firm, smooth, and can sometimes be hereditary.

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research Cutaneous Adnexal Cysts Revisited: A Novel Classification Based on Morphological and Molecular Features

April 2018 in “Journal of Investigative Dermatology”

The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.

research Immunohistochemical Study of Calretinin in Normal Skin and Cutaneous Adnexal Proliferations

34 citations , February 2012 in “American Journal of Dermatopathology”

Calretinin can help identify certain skin structures and tumors.

research Cutaneous Adnexal Cysts Revisited: What We Know and What We Think We Know

13 citations , June 2018 in “Dermatopathology”

A new classification system for skin cysts was proposed to improve diagnosis.

research Clinicopathological Factors Associated With Trichilemmal Cysts

November 2025 in “JPRAS Open”

Age and diabetes are linked to larger trichilemmal cysts, while hypertension is linked to smaller ones.

research Specific In Vivo Ablation of Lrig1-Positive Follicular Stem Cells Results in Sebaceous Gland Loss in Mice

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.

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