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GlossaryTrichoblastoma

rare benign tumor from hair follicle cells

Trichoblastoma is a rare, benign skin tumor that originates from the hair follicle cells. It typically appears as a small, slow-growing nodule on the scalp or face and is composed of cells that resemble the primitive hair matrix, making it important for dermatologists to distinguish it from more aggressive skin cancers.

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research Cytokeratin Expression in Trichoblastic Fibroma, Trichoepithelioma, and Basal Cell Carcinoma

87 citations , January 1999 in “British Journal of Dermatology”

Trichoblastic fibroma and basal cell carcinoma are similar but different from trichoepithelioma.

research Merkel Cell Differentiation in Trichoblastoma

34 citations , January 1998 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

Trichoblastomas may mimic fetal skin development by having many Merkel cells, unlike adult skin.

research Trichoblastoma of the Breast Detected by Screening Mammography: A Diagnostic Pitfall

6 citations , April 2010 in “The American Journal of Surgical Pathology”

Trichoblastoma in the breast can be mistaken for cancer, so expert review is crucial to avoid misdiagnosis.

research Melanotrichoblastoma: A Histopathological Case Report of a Rare Pigmented Variant of Trichoblastoma

2 citations , August 2025 in “Reports — Medical Cases Images and Videos”

A rare pigmented skin tumor called melanotrichoblastoma was diagnosed in a 51-year-old woman.

research Trichoblastic Carcinoma: Case Study of Deeply Infiltrative Neoplasms

2 citations , July 2001 in “Dermatologic Surgery”

Trichoblastic carcinoma may be a distinct type of skin cancer different from basal cell carcinoma.

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