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research Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin

March 2025 in “Scientific Reports”

This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.

research Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition From Telogen to Anagen Phase

5 citations , March 2022 in “Frontiers in Cell and Developmental Biology”

This study found that exosomes derived from bovine colostrum promoted hair growth in mice by activating the Wnt/β-catenin pathway, with effects similar to minoxidil but without adverse effects.

Ginsenosides in Panax Ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation

research Ginsenosides in Panax ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation

January 2024 in “Biological & pharmaceutical bulletin”

In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.

research Zwischen Tradition und Innovation Historische Plätze in der Bundesrepublik Deutschland nach 1945

1 citations , January 2004

This review discusses epithelial-mesenchymal interactions in hair follicle development and their regulation by molecular signals, but reports no new results; the authors emphasize the need for further research to apply these findings clinically.

research Kartogenin regulates hair growth and hair cycling transition

2 citations , January 2022 in “International Journal of Medical Sciences”

In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.

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Community Join

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community How to transition from Fin to DUT?

in Finasteride/Dutasteride 9 upvotes 1 month ago

The user switched from oral finasteride and topical minoxidil to oral minoxidil and dutasteride, seeing improvements in hair growth. Most users suggest continuing with dutasteride and possibly phasing out finasteride, as dutasteride is a stronger DHT blocker.

community 20 years old: 6 months of 1MG Fin + 1 month back on topical Min - Shed phase sucks.

in Progress Pictures 23 upvotes 1 month ago

A 20-year-old is experiencing hair thinning after 6 months on finasteride and 1 month on topical minoxidil, noting a difficult shedding phase. Others suggest patience and possibly considering dutasteride if needed, while emphasizing the importance of gradual transitions between treatments.

community Oral 1mg Fin/ 2.5mg Min (Before/After)

in Progress Pictures 127 upvotes 7 months ago

The conversation discusses hair loss treatments, specifically the transition from topical to oral minoxidil and finasteride, and the associated shedding phase. Users advise patience and consistency, noting that shedding is common and improvement may take several months.

community Transition from Baby Hair to Normal Hair?

in Finasteride/Dutasteride 33 upvotes 2 years ago

The conversation discusses the slow transition from baby hair to normal hair while using finasteride and transitioning to dutasteride, with progress except for the crown area. It's mentioned that hair thickening can take years, with each growth cycle potentially making the hair thicker, and this process can span over 6 months or more.

community Transitioned from topical minoxidil to oral min and the shedding is crazy!

in Minoxidil 243 upvotes 8 months ago

Switching from topical to oral minoxidil can cause initial hair shedding but may lead to thicker hair growth. Many users combine it with finasteride, experiencing varying side effects.

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Learn

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learn HMI-115

Who can benefit the most from HMI-115: men, women, or people in transition? There is no published trial showing that any one group benefits most from HMI-115: the only released human efficacy data is a company press release on a 16-person Phase 1b, and it reported hair-count results for the 12 men only.

learn Stemoxydine

How does stemoxydine help stimulate new hair growth on the scalp? Stemoxydine stimulates new hair growth by promoting hair follicles to transition from the resting phase to the active growth phase.

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Cyproterone

Is cyproterone safe to use during gender transition? Regulators and a large French cohort study link higher-dose, long-term cyproterone acetate to meningioma, and its label also lists liver-enzyme and mood effects — so it is not a drug anyone should call safe in the abstract, and its use in gender-affirming care is a prescriber's decision with monitoring.

learn Setipiprant

Can Setipiprant be used safely by women or people undergoing gender transition? Setipiprant's safety for women and those in transition is not well-studied.

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