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research The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial

57 citations , August 2003 in “British Journal of Dermatology”

This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.

research Interspecies variations in response to topical application of selected zinc compounds

49 citations , January 1991 in “Food and chemical toxicology”

In this study, zinc chloride was found to be severely irritant to the skin in rabbit, guinea-pig, and mouse models, while zinc oxide, zinc sulphate, zinc pyrithione, and zinc undecylenate showed minimal to no irritancy.

research Zinc Therapy in Dermatology: A Review

165 citations , January 2014 in “Dermatology Research and Practice”

This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.

research Efficacy of Off-Label Topical Treatments for the Management of Androgenetic Alopecia: A Review

5 citations , January 2019 in “Clinical Drug Investigation”

This study found that certain off-label topical therapies, including prostaglandin analogs and polyphenols, improved hair restoration in men with androgenetic alopecia over placebo in the short term, though long-term effects are unknown.

research In-Vitro Release of Zinc Pyrithione from A Shampoo Base and the Effects of Various Additives on its Release Rate

3 citations , January 1985 in “Drug development and industrial pharmacy”

In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.

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community Zinc Pyrithione for pattern hair loss.

4 upvotes 5 years ago

Zinc pyrithione and ketoconazole shampoos may help reduce hair loss by removing DHT from the scalp. Users discuss various treatments, including minoxidil, finasteride, and non-pharmaceutical options like castor oil and dermarolling.

community Ketoconazole vs Ciclopirox which one was better for you ?

3 upvotes 1 year ago

Switching from ketoconazole to a ciclopirox and zinc pyrithione shampoo significantly reduced hair fall. The user is considering whether to continue using ketoconazole occasionally or combine both shampoos weekly.

community I'm on multiple anti-androgens and after around year, my hairs are thinner, why?

in Finasteride/Dutasteride 16 upvotes 3 years ago

The user has been using finasteride, dutasteride, pyrithione zinc, and oral minoxidil to treat hair loss and has seen an increase in fine hairs on the hairline but overall thinning on the top. They are considering adding zinc and Vitamin K to their regimen and are already taking hair multivitamins with collagen.

community I Recovered From Severe Hair Loss: My 8-Month Regrowth Recovery — Full Timeline, Photos & Treatment Data

35 upvotes 4 months ago

A 29-year-old male experienced significant hair regrowth over 8 months using a protocol of oral Minoxidil, Dutasteride, Pyrithione Zinc Shampoo, and peptides GHK-CU, BPC-157, and TB-500. The treatment led to improved scalp coverage, reduced hair loss, and thicker hair, although results may vary for others.

community Handle the itch from Minoxidil?

in Minoxidil 1 upvotes 5 months ago

Minoxidil can cause scalp itchiness, often due to propylene glycol, and users suggest alternatives like foam formulations without PG, using moisturizing oils, or reducing application frequency. Some recommend ketoconazole or zinc pyrithione shampoos to help with inflammation and itchiness.

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