pyrithione
Research
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research The Effects of Minoxidil, 1% Pyrithione Zinc, and a Combination of Both on Hair Density: A Randomized Controlled Trial
This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.
research Does Tachyphylaxis Occur in Long-Term Management of Scalp Seborrheic Dermatitis with Pyrithione Zinc-Based Treatments?
This study concluded that no evidence of tachyphylaxis was found in the treatment of scalp seborrheic dermatitis and dandruff using pyrithione zinc-based shampoos over a 48-week period.
research Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations
This study found that 1% ketoconazole and 1% piroctone olamine shampoos increased hair shaft thickness and reduced hair shedding in men with telogen effluvium and androgenic alopecia associated with dandruff.
research Targeted Delivery of Zinc Pyrithione to Skin Epithelia
This review details how zinc pyrithione's anti-fungal activity makes it a successful treatment for dandruff and seborrheic dermatitis, by effectively targeting Malassezia yeast in the scalp.
research Ex-Vivo Measurement of Scalp Follicular Infundibulum Delivery of Zinc Pyrithione and Climbazole from an Anti-Dandruff Shampoo
In this study, researchers developed a method using scalp cyanoacrylate biopsy and advanced imaging techniques to effectively measure and visualize the distribution of anti-dandruff shampoo ingredients zinc pyrithione and climbazole within the scalp follicular infundibulum.
research Multi-Modal Imaging to Assess the Follicular Delivery of Zinc Pyrithione
This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.
research In Vitro Release of Zinc Pyrithione from a Shampoo Base and the Effects of Various Additives on Its Release Rate
In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.
research Study on the Effectiveness of Zinc Pyrithione in Anti-Dandruff Shampoo Formulations
This study reviewed existing literature and reported that 1% Zinc pyrithione in anti-dandruff shampoo effectively inhibits the growth of fungi responsible for dandruff, aligning with the regulatory limits set by Indonesian health authorities.
research The Effect of a Novel Zinc Pyrithione Hair Care System on Female Scalp Condition
The zinc pyrithione hair care system improves scalp hydration and reduces water loss.
research The Effects of Zinc Pyrithione on Dandruff and Itch
This study found that using a zinc pyrithione-containing hair rinse significantly reduced dandruff and itching, with effects linked to the amount of zinc pyrithione residue on the hair.
research The Use of Autoradiography to Study the Localization of Germicides in Skin
This study used an autoradiographic technique to observe that germicides in surfactants are primarily deposited on the stratum corneum of guinea-pig and human skin.
research A Comparison of Hair Quality and Cosmetic Acceptance Following the Use of Two Anti-Dandruff Shampoos
Most women preferred the 1% pyrithione zinc shampoo for better hair smoothness and less frizz while controlling dandruff.
research Product Pharmacology and Medical Actives in Achieving Therapeutic Benefits
Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.
research Efficacy of Off-Label Topical Treatments for the Management of Androgenetic Alopecia: A Review
This study found that certain off-label topical therapies, including prostaglandin analogs and polyphenols, improved hair restoration in men with androgenetic alopecia over placebo in the short term, though long-term effects are unknown.
research Alopecia in a 19-Month-Old Boy
This article reports a case of a 19-month-old boy with scalp erythematous papules and hair loss, showing no improvement with initial treatment.
research Zinc Therapy in Dermatology: A Review
This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
research Interspecies Variations in Response to Topical Application of Selected Zinc Compounds
In this study, zinc chloride was found to be severely irritant to the skin in rabbit, guinea-pig, and mouse models, while zinc oxide, zinc sulphate, zinc pyrithione, and zinc undecylenate showed minimal to no irritancy.
research New Insights on Dandruff/Seborrhoeic Dermatitis: The Role of the Scalp Follicular Infundibulum in Effective Treatment Strategies
This study found that certain zinc pyrithione shampoos effectively deliver antifungal agents to the scalp's follicular infundibulum, correlating with reduced Malassezia populations, likely influenced by particle size optimizing such delivery.
research Scalp Condition Impacts Hair Growth And Retention Via Oxidative Stress
This article reviews the relationship between scalp conditions and hair health, suggesting that shampoos with Malassezia inhibitory agents may help reduce premature hair loss, but it presents no new clinical results.
research Zinc in Skin Pathology and Care
This review found little evidence supporting zinc as a first-line treatment for dermatological conditions, except in cases of systemic zinc deficiency, and suggests further research is needed.