This study found that various reduced folates effectively penetrated an in vitro skin model, promoted cell proliferation and migration, and may enhance wound healing, suggesting potential for topical treatment in skin conditions.
April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that new folate salts in aqueous and lipophilic solutions can penetrate skin and enhance wound healing in vitro by converting metabolically, suggesting their potential for topical application.
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January 2000 This chapter discusses various substances and therapies for dermatological applications, including heliotherapy, UVB, khellin, and others, but reports no new research findings.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” In this report, a 46-year-old woman's sudden diffuse hair loss was diagnosed as granulomatous alopecia areata, with spontaneous hair regrowth observed after two months. This case highlights that granulomatous inflammation should not exclude the diagnosis of alopecia areata, emphasizing the importance of clinicopathological correlation.
October 2025 in “Turkish Journal of Biochemistry” This study found that patients with tropical chronic pancreatitis exhibited significantly reduced plasma amino acid levels and antioxidant capacity, with folate deficiency identified as a key factor in hyperhomocysteinemia.