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research Trigonelline nanocrystal-based topical creams for the treatment of hair loss

October 2024 in “Journal of Advanced Pharmaceutical Technology amp Research”

This study found that nanoparticulate trigonelline formulations significantly improved hair length and density in rats with induced alopecia compared to controls and commercial hair oil, though it was not more effective than minoxidil after 30 days.

research Preparation and Physicochemical Evaluation of Topical Cream Ivermectin 1% for Treatment of Rosacea

November 2023 in “Dermatology Research and Reports”

This study reported that a 1% ivermectin topical cream for rosacea was stable over six months, showing no significant changes in key physical properties or microbial contamination, suggesting it may reduce chronic antibiotic use in rosacea treatment.

research Topical Administration of 15‐Deoxy‐Δ^12,14‐Prostaglandin J₂ Using a Nonionic Cream: Effect on UVB‐Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

9 citations , January 2021 in “Mediators of Inflammation”

In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.

research Successful Treatment of Lichen Spinulosus with Topical Tacalcitol Cream

11 citations , August 2010 in “Pediatric dermatology”

This report details two cases of Lichen spinulosus in the submental area, treated effectively and safely with topical tacalcitol cream.

Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream

34 citations , October 2014 in “European journal of pharmaceutics and biopharmaceutics”

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

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Community Join

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community How to mix topical tretinoin spray from cream

3 upvotes 3 years ago

Mixing tretinoin cream with minoxidil for hair loss treatment. Tretinoin enhances minoxidil's effectiveness for androgenic alopecia.

community Started 2.5 mg oral min 3 months ago (3+ years on oral fin/ topical min) & was just prescribed .025% tretinoin cream

in Treatment 5 upvotes 1 year ago

The user has been using oral finasteride and topical minoxidil for years and recently started 2.5 mg oral minoxidil, with no significant regrowth observed yet. They are considering adding tretinoin cream to their regimen but are concerned about potential shedding.

community Putting antihistamine cream on scalp to fight inflammation and itchy scalp?

2 upvotes 3 years ago

Topical antihistamine creams, like diphenhydramine, are being considered for scalp inflammation and itchiness as an adjunct to standard hair loss treatments like minoxidil and finasteride. The user is cautious about oral antihistamines due to potential side effects and is exploring topical options.

community 3 months progress - topical Fin/Min (Canada)

in Progress Pictures 156 upvotes 1 year ago

The user experienced significant hair regrowth using a topical finasteride and minoxidil cream from Essential Clinic in Canada, and plans to switch to dutasteride and undergo a hair transplant in Mexico. They started treatment three months ago and have seen impressive results without side effects, using half the recommended dosage to extend the product's duration.

community Can topical Minoxidil use backfire if you’re a non-responder?

1 upvotes 3 months ago

The user has been using finasteride successfully to stop hair shedding and is considering using topical minoxidil for regrowth but is concerned about being a non-responder and potential negative effects. They are cautious about using oral minoxidil due to past heart issues and are exploring other methods like tretinoin cream and dermarolling, though they worry about possible skin damage.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small unblinded pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin primarily hydrates hair but does not increase thickness or follicle function.

learn L-cysteine

Can topical products with L-cysteine repair damaged hair or prevent breakage? Topical L-cysteine cannot effectively repair damaged hair or prevent breakage.

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