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Glossary Topical Anesthetic Cream

medication applied to skin to temporarily numb the area

Topical Anesthetic Cream, often referred to as numbing cream, is a medication applied to the skin to temporarily numb the area. It works by blocking nerve signals in the body, making it useful for reducing pain or discomfort during minor medical procedures, such as injections, laser treatments, or minor surgeries. Common active ingredients include lidocaine or benzocaine.

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Research

5 / 1000+ results

research Effect of Topical Anesthetics on Pain Perception during Scalp Platelet-rich Plasma Injections

July 2026 in “Current Medical Issues”

In this study, using EMLA cream did not adequately control pain during and after scalp PRP injections for androgenetic alopecia, with anxiety and younger age linked to higher pain levels.

research Topical Melatonin in Aesthetic Dermatology: From Cutaneous Melatoninergic Biology to Photoprotection, and Skin Rejuvenation

July 2026 in “Clinics in Dermatology”

This review discusses the potential benefits of topical melatonin in aesthetic dermatology, including its antioxidant and protective properties for skin aging and photoaging, while also noting varying strengths of evidence across different skin conditions.

A Preliminary Study on the Application of a Vibrating Device Instead of Topical Anesthetic Gel During Injection of Local Anesthesia

research A Preliminary Study on Application of Vibrating Device Instead of Topical Anaesthetic Gel During Injection of Local Anaesthesia

August 2020 in “Bioscience Biotechnology Research Communications”

This study found that using topical anesthetic was more effective than a vibrating device in reducing discomfort from dental injections.

research Topical minoxidil effectiveness in enhancing facial aesthetics: A systematic review and meta-analysis

November 2025 in “Journal of Family Medicine and Primary Care”

This systematic review and meta-analysis found that low-dose minoxidil treatment effectively enhances facial hair development with relatively minimal side effects, which can be beneficial in primary care settings.

research Local Anesthesia Techniques in Hair Restoration Surgery

3 citations , May 2016 in “Journal of Cutaneous Medicine and Surgery”

This article briefly describes local anesthesia techniques for hair restoration surgery that aim to enhance patient comfort but reports no new research results.

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Community Join

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community Why not use hair system instead of Topical Hassle

in Hair Systems 18 upvotes 1 year ago

Topical treatments like minoxidil and finasteride are preferred for hair loss due to ease of use and natural appearance. Hair systems are considered high-maintenance and less genuine.

community Topical finasteride making. Powder not disolving

4 upvotes 3 years ago

OP is trying to dissolve finasteride powder for a topical solution but faces issues with it not dissolving properly in ethanol or water. Users suggest methods like using a magnetic stirrer, shaking the mixture, or filtering out fillers, with some noting that finasteride is soluble in alcohol.

community Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth

24 upvotes 1 year ago

Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.

community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid

6 upvotes 1 year ago

Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

community Topical Metformin for Hair Transplant donor area skin/hair regeneration?

4 upvotes 1 year ago

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

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Learn

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learn Overview

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small unblinded pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin primarily hydrates hair but does not increase thickness or follicle function.

learn L-cysteine

Can topical products with L-cysteine repair damaged hair or prevent breakage? Topical L-cysteine cannot effectively repair damaged hair or prevent breakage.

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