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research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride

1 citations , October 2023 in “Journal of personalized medicine”

In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.

research Bioequivalence study of generic finasteride in healthy male volunteers.

2 citations , September 2011 in “Chiang Mai Medical Journal - เชียงใหม่เวชสาร”

This study demonstrated that the 5-mg generic finasteride tablet is bioequivalent to the original tablet when tested in healthy Thai male volunteers.

research Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics

January 2003 in “The Chinese Journal of Clinical Pharmacology”

In this study, an LC/MS/MS method was successfully developed to determine finasteride concentrations and study its pharmacokinetics in healthy male Chinese volunteers.

research Study on Human Bioequivalency of Two Preparations of Finasteride

January 2005 in “Journal of Elinical Research”

This study found that the pharmacokinetic profile of finasteride capsules and tablets in healthy volunteers is bioequivalent.

research Bioequivalance of single oral administration of finasteride tablet and capsule in healthy volunteers

January 2004

This study found that the finasteride tablet and capsule are bioequivalent to the control finasteride tablet in healthy volunteers.

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community Microneedling must reach the stem cells in the upper hair shaft

82 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community How would you react if PP405 isn't successful in phase 3 trials?

in Chat 23 upvotes 9 months ago

People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

community Don’t spend too much time on this Subreddit if you’re just starting

in Chat 157 upvotes 1 year ago

Avoiding excessive time on hair loss forums to reduce anxiety and focus on consistent use of treatments like finasteride and minoxidil. Users emphasize trusting medical advice, being patient for results, and not overanalyzing anecdotal experiences.

community Story time! The Great Unbalding (PP405)

230 upvotes 11 months ago

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

community Can pp405 revive dead follicles for long time bald people? Are those even dead? After 10+ years bald

47 upvotes 1 year ago

PP405 may revive dormant hair follicles but is unlikely to help with long-term baldness where follicles are replaced by scar tissue. It is seen as a potential adjunct to treatments like minoxidil and finasteride, but its effectiveness on deeply fibrotic or scarred areas is doubtful.

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