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research LB789 Novel IFNγ Aptamer TAGX-0003 Protected Hair Follicles from Immune Privilege Collapse and Reversed Alopecia Areata-Like Phenotype in Humanized Mouse Model

August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.

research Autoimmunity: Alopecia Areata

143 citations, January 2004 in “Journal of Investigative Dermatology Symposium Proceedings”

Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.

Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study

research Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study

10 citations, April 2020 in “Dermatology and therapy”

Calcipotriol works almost as well as clobetasol for mild to moderate alopecia areata with fewer side effects.

research Cancer Risk by the Subtype of Alopecia

9 citations, June 2018 in “Scientific Reports”

People with certain types of alopecia have a slightly higher risk of cancer, especially thyroid, bladder, and prostate cancers.

research Evaluation of Serum Levels of IL-6, IL-10, and TNF-a in Alopecia Areata Patients: A Systematic Review and Meta-Analysis

6 citations, October 2021 in “Biomedical Research and Therapy”

Alopecia areata patients have higher levels of IL-6 and TNF-α.

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community When someone posts a scalp tension theory

in Satire 265 upvotes 3 years ago

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.