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5 / 689 results![1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta](/images/research/13e3cb41-1fc5-4714-bb71-839fa26fcb36/small/19436.jpg)
research 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
![Wound Healing: A Cellular Perspective](/images/research/9dde12dd-3934-4b3b-bec6-e0b163969845/small/19385.jpg)
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
![Genetic, hormonal and metabolic aspects of PCOS: an update](/images/research/15741944-bb4b-4783-860b-72637400d1c4/small/20971.jpg)
research Genetic, hormonal and metabolic aspects of PCOS: an update
The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
![Transforming growth factor-β in stem cells and tissue homeostasis](/images/research/4d38f480-144e-4334-af2c-4d1b50204625/small/19469.jpg)
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
![Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot](/images/research/34c8a798-10a7-4b5a-8157-099a79cf9af9/small/35694.jpg)
research Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
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5 / 14 resultscommunity Hairloss - what hormones to check?
The user is concerned about hair loss despite using oral finasteride, oral minoxidil, and topical minoxidil. They are seeking advice on additional blood tests to identify potential causes.
community HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community TGF-Beta. Good or Bad? Help for treatment investment
TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.
community Tretinoin potentially can make hair loss worse ?
Tretinoin may worsen hair loss by inducing premature hair follicle regression. It can be used with minoxidil to increase absorption but should not be used alone.
community 5 Month’s progress on Topical FIN, MIN, Topical Dut, Laser Cap
User "hemantch" shares 5 months progress using topical Fin, Min, topical Dut, and a laser cap for hair loss. Significant regrowth was noticed after 1 month, and the treatments worked well despite being bald for 10 years.