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research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research

12 citations , January 2021 in “Journal of Investigative Dermatology”

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

research Conditional Telomerase Induction Causes Proliferation of Hair Follicle Stem Cells

414 citations , August 2005 in “Nature”

Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.

research Novel In Vitro Culture Condition Improves the Stemness of Human Dermal Stem/Progenitor Cells

18 citations , November 2013 in “Molecules and Cells”

New culture method keeps human skin stem cells more stem-like.

research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

5 citations , August 2019 in “iScience”

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

research Opposing Impacts on Healthspan and Longevity by Limiting Dietary Selenium in Telomere Dysfunctional Mice

30 citations , September 2016 in “Aging Cell”

Low selenium levels can extend lifespan but worsen health issues.

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Community Join

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community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 2 years ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

in Research/Science 42 upvotes 1 year ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community Is this real chat? Finasteride -> fountain of youth and longevity drug?

in Finasteride/Dutasteride 558 upvotes 6 months ago

Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.

community Hair loss research is a money grab

in Chat 225 upvotes 4 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community M26 - 9 months after hair transplant! AMA

in Transplants 624 upvotes 6 years ago

A user who underwent a hair transplant in Istanbul to reduce balding, and the discussion of various treatments such as finasteride and growth hormone for preventing further hair loss.

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