414 citations
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August 2005 in “Nature” In this study, researchers discovered that activating TERT in mouse skin epithelium triggers dormant hair follicle stem cells, leading to rapid hair growth, through a pathway independent of telomere extension.
October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that induced TERT expression in mouse skin epithelium rapidly transitions hair growth from the resting to active phase by promoting stem cell proliferation through a non-telomere related mechanism.
145 citations
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May 2008 in “Cancer Science” This review discusses how increased gene copy number for telomerase components may contribute to telomerase up-regulation in cancer cells, although the exact mechanisms are not fully understood.
22 citations
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October 2020 in “Frontiers in Cell and Developmental Biology” This study found that resveratrol and fisetin promoted hair growth in mice by inducing telomerase reverse transcriptase expression, which activates hair follicle stem cells and transitions follicles from a resting to a growth phase.
5 citations
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January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.